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The study was designed not only to determine blood alcohol levels by time but also to examine the changes of working ability after ingestion of alcohol. Twelve healthy students aged from 21 to 25 volunteered as subjects for this study. All subjects were instructed to fast at least 4 hours prior to testing, Liquor in concentration of 45% ethanol was administered with the amount of 1 ml of ethanol per ㎏ of body weight to the subjects. Blood samples were taken regularly at 15, 30, 60, 90, 120 and 180 minutes after the administration of alcohol and the concentration of alcohol in the blood were determined by the Widmark method. Performance of the subjects by choice reaction test, eye-hand coordination test and Kraepelin test were examined at the same time when each blood samples was taken. Additionally, by administering the equivalent amount of alcohol with liquor(45% ethanol) and beer(4%ethanol), the blood alcohol level changes by time after ingestion of alcohol was observed. The results obtained can be summarized as follows. 1. Mean blood alcohol level changes resulting from administration of 1 ml of ethanol per ㎏ of body weight were 0.09% (90%±23㎎/100ml), 0.10%(104±27㎎/100ml), 0.14% (104±27㎎/100ml), 0.17% (171±49㎎/100ml), 0.12%(117±46㎎/100ml) and 0.09% (86±23㎎/100ml) at the 15, 30, 60, 90, 120 and 180 minutes after the administration respectively. The peak in the concentration of blood alcohol was reached at 90 minutes after the ingestion. 2. In choice reaction test, reaction times became prolonged as blood alcohol levels increased. The reaction time showed a significant changes when the blood alcohol concentration reached 0.09 percent or more from the control group. 3. In eye-hand coordniation test, the accuracy of the performance became decreased as blood alcohol levels increased. The accuracy of eye-hand coordination differed significantly from control group when the blood alcohol levels reached 0.09 percent or more after alcohol ingestion. 4. In Kraepelin test, the abilities of calculation also became lowered as blood alcohol levels increased. The difference of abilities of calculation was shown when a alcohol levels of 0.09 percent or more. 5. Blood alcohol levels resulting from administration of alcohol in combination of liquor and beer, though the total amount of ingestion was equivalent (1 ml/㎏ of body wt.), showed a tendency of higher levels in blood alcohol comparing with those when liquor alone was administered. Nevertheless, this was not a significant difference between the two groups. Further investigation ought to be done clarify this matter.
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